A dose of ultrasound to
the testicles can stop the production of sperm, according to researchers
investigating a new form of contraception.
A study on rats published in Reproductive Biology and
Endocrinology showed that sound waves could be used to reduce sperm
counts to levels that would cause infertility in humans.
Researchers described ultrasound as a "promising candidate" in contraception.
However, far more tests are required before it could be used.
The concept was first proposed in the 1970s, but is now being
pursued by researchers at the University of North Carolina who won a
grant from the Bill & Melinda Gates Foundation.
They found that two, 15-minute doses "significantly reduced" the number of sperm-producing cells and sperm levels.
It was most effective when delivered two days apart and through warm salt water.
In humans, the researchers said men were considered to be
"sub-fertile" when sperm counts dropped below 15 million sperm per
millilitre.
The sperm count in rats dropped to below 10 million sperm per millilitre.
Lead researcher Dr James Tsuruta said: "Further studies are
required to determine how long the contraceptive effect lasts and if it
is safe to use multiple times."
The team needs to ensure that the ultrasound produces a
reversible effect, contraception not sterilisation. As well as
investigate whether there would be cumulative damage from repeated
doses.
Dr Allan Pacey, senior lecturer in andrology at the
University of Sheffield, said: "It's a nice idea, but a lot more work is
needed."
He said that it was likely that there would be recovery of
sperm production, but the "sperm might be damaged and any baby might be
damaged" when sperm production resumed.
"The last thing we want is a lingering damage to sperm," he said.
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